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Evvy vs URO

Evvy vs URO: Which Probiotic Is Better for Women’s Health?

Comparing Evvy vs URO? Discover which probiotic better supports women’s health with a deep dive into ingredients, benefits, and formulation differences.

Last updated on Jul 30, 2025

Words by Olivia Cassano

Scientifically edited by Pita Navarro

Medically reviewed by Dr. Kate McLean MD, MPH, FACOG

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If you’re exploring probiotics for vaginal health, chances are you’ve come across both Evvy and URO. Whether you’re dealing with yeast infections, recurring UTIs, or just want to maintain a healthy vaginal microbiome, finding the right probiotic can feel overwhelming.

Both brands offer options aimed at supporting vaginal health, but they take very different approaches. URO focuses on symptom relief, like odor and discharge. Evvy’s Women’s Complete Probiotic is built to support not just the vaginal microbiome, but also the gut and urinary systems, all in one capsule.

In this article, we’ll compare the two side by side, breaking down differences in formulation, benefits, testing, and more, so you can choose the option that best fits your body and goals.

Key insights before buying Evvy or URO probiotics

Here’s what to keep in mind as you compare these two options:

  • Evvy’s Women’s Complete Probiotic is designed for those looking to support the vaginal, urinary, and gut microbiomes with a single capsule backed by scientific research.
  • URO Probiotic by O Positiv is a vaginal health supplement focused on yeast balance, odor control, and maintaining a healthy vaginal pH.
  • Evvy’s probiotic is informed by the largest real-world vaginal microbiome dataset, allowing the team to select clinically validated strains that target the root causes of imbalance. Instead of simply masking symptoms, it’s designed to help improve and maintain a healthier microbiome for the long term.
  • URO contains four probiotic strains plus cranberry extract, zinc, and ascorbic acid, with a more targeted focus on symptoms like odor and discharge.
  • Neither requires refrigeration, and both are available via subscription.

Overview of both probiotics

Evvy Women’s Complete Probiotic

Evvy’s Women’s Complete Probiotic offers advanced 3-in-1 microbiome support for your gut, urinary tract, and vaginal health, all in one capsule. Unlike most probiotics that focus only on digestion or symptom relief, Evvy’s formula is deeply rooted in science and built from the largest real-world vaginal microbiome dataset ever assembled.

With strains like Lactobacillus crispatus, Evvy Women’s Complete Probiotic is formulated with stains clinically proven to support the growth of protective bacteria while helping reduce the risk of UTIs, maintain vaginal pH, and promote gut balance. The delayed-release capsule ensures more probiotics reach the gut alive, without refrigeration.

Pros & cons

Pros:

  • Supports vaginal, urinary, and gut microbiomes
  • Includes clinically studied strains backed by real-world data
  • Built specifically for women’s health
  • Once-daily capsule, no refrigeration
  • Transparent testing for quality, allergens, and heavy metals.

Cons: 

  • It’s not a replacement for medical treatment
  • As with most microbiome-supportive products, results may take time.

URO Probiotic by O Positiv

URO is marketed as a vaginal health probiotic with a focus on yeast balance, discharge, and odor control. It includes four probiotic strains along with supportive ingredients like cranberry extract (often associated with urinary tract health), zinc, and ascorbic acid.

URO is a good match for people looking for targeted relief, though it doesn’t holistically support the urinary or gut microbiomes in the same way Evvy does.

Pros & cons

Pros:

  • Targets odor, yeast, and vaginal pH
  • Simple daily routine with one capsule
  • Contains supportive nutrients (zinc, cranberry, vitamin C)

Cons:

  • Focused only on vaginal health
  • Lacks urinary or gut-specific strains
  • Less detailed transparency about clinical data or testing
  • It’s not a replacement for medical treatment
  • As with most microbiome-supportive products, results may take time. 

Main differences between Evvy and URO probiotics

While both aim to support vaginal health, their scope and formulation differ:

  • Evvy supports the full female microbiome (vaginal, urinary, and gut systems) with strains chosen from extensive microbiome research.
  • URO supports vaginal concerns like odor or yeast imbalance but doesn’t offer broader microbiome or gut support.
  • Evvy’s data-driven approach and testing practices offer a higher level of scientific transparency than most supplements in the category. Our Women’s Complete Probiotic is backed by the largest real-world dataset on the vaginal microbiome. Every ingredient is meticulously chosen by our scientists based on the latest available research, including our own proprietary findings.

What is better, Evvy or URO?

The answer depends on your health goals. If you’re looking for targeted vaginal symptom relief URO is a solid, straightforward option. But if you want to support your whole microbiome, including vaginal, urinary, and gut health, Evvy offers a more comprehensive, science-backed solution. Because your microbiomes don’t operate in isolation, neither should your probiotic

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