Anti-Itch Vulva Cream

Get fast-acting relief from external itching & irritation — formulated with hydrocortisone, aloe, and Vitamin E.

Safe for sensitive skin and formulated with hydrocortisone, aloe, and vitamin E, our Anti-Itch Cream quickly calms symptoms while promoting antioxidant nourishment and cell regeneration.

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30 doses (6 gram tube)

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$59.00

$53.10

6 gram tube every 2 months
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Max 6 units

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HSA/FSA Eligible

This is a prescription product. A licensed, Evvy-affiliated provider will determine your prescription at their sole discretion.

Ingredients

5% hydrocortisone, aloe vera, vitamin E, Ketotifen .25%, hypoallergenic cream base, Ethoxy

Allergens: aloe, hydrocortisone

How to Use

Apply 4 clicks of cream onto the external vulvar area as needed, up to 3 times per week.

Do not use inside the vagina. This medication is not intended to be used at maximum dosage long term. Use within 180 days of purchase.

Quality & Safety

At Evvy, we’re committed to giving you the safest, most effective care—so we use only prescription-grade, non-toxic ingredients that are free from harmful additives.

Non-Toxic
No PFAs
No Parabens
No BPAs
No Phthalates
No GMOs
No Sulfites
No Artificial Colors/Fragrances/Dyes

Please note that our Rx Symptom Relief products can help manage symptoms, but are not being prescribed to treat an underlying condition. They are ideal for use alongside Evvy’s vaginal microbiome test and Complete Treatment Programs, which can help uncover and target the root causes of symptoms.

This is a compounded medication, formulated in a 503a NABP-accredited pharmacy. Compounded products are not approved by the FDA.

Eligibility

Your specific prescriptions will be determined at the sole discretion of an Evvy-affiliated provider. To ensure safe, compliant, and personalized care, we cannot prescribe this treatment for patients who are:

Pregnant or trying to become pregnant
Breastfeeding
Younger than 18 or older than 80 years old

This treatment is not yet available in Canada or the following US states: Arkansas, Delaware, Kansas, Mississippi, New Mexico, Puerto Rico, Rhode Island, South Carolina, Vermont, US Virgin Islands, Washington DC, West Virginia, Armed Forces Europe / Pacific

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developed by researchers + OB/GYNs

Uniquely formulated for women

science-backed ingredients

No harsh additives

Why Anti-Itch Vulva Cream

Quickly calm itching & irritation

Relieve itching fast

Soothe irritation and inflammation

Restore comfort

Why our formulation

Fast-acting relief for sensitive skin

Hydrocortisone

Relieves itching & calms inflammation

Hydrocortisone has been used for decades to treat vaginal and vulvar itch and inflammation. Topical hydrocortisone can calm your body's local immune response, leading to reduced redness, swelling and irritation.

Pure Aloe

Soothes irritation

Aloe is both an antioxidant and an anti-inflammatory, making it the perfect addition to our soothing formulation. Research shows aloe can be as effective as estrogen for relief of vaginal dryness.

Vitamin E (Vulva Cream)

Supports hydration & comfort

Vitamin E soothes irritation, supports mucosal repair, and improves tissue comfort.

It has also been shown to improve symptoms by supporting blood flow and keeping blood vessels flexible. This can increase blood flow which boosts the overall health and moisture of vaginal tissues.

Backed by science & designed by OB-GYNs

From research on the same active ingredients:

100%

reported relief within 2-3 hours with hydrocortisone (Blinick 1955).

76%

reported symptom improvement with Vitamin E (Emamverdikhan 2016).

How It Works

Step 1

Order your Rx from Evvy

All Evvy prescription (Rx) products are custom compounded at a 503a NABP-accredited pharmacy, ensuring clean and safe ingredients.

Step 2

Complete your intake form

A licensed, Evvy-affiliated provider will review your order and intake form within 24 hours. We’ll reach out to you over email if there are any questions.

Step 3

Rx shipped to your door

If prescribed, your prescriptions will be shipped straight to you and typically arrive within 3-6 business days.

Step 4

Test with Evvy for root cause

Evvy’s products are designed to relieve symptoms, not treat underlying conditions. Taking an Evvy test gives you a complete picture of your vaginal health and empowers you to address root causes, not just symptoms.

From the community

Providers and patients choose Evvy

"Formulated for quick relief, Evvy’s Anti-Itch Vulva Cream calms itching and inflammation with a fast-acting, effective blend of hydrocortisone and soothing ingredients. We know how disruptive symptoms can be—this cream helps you find comfort fast."

Dr. Kate McLean, MD, MPH, FACOG

Chief Medical Advisor, Evvy

"[Evvy's Anti-Itch Vulva Cream] is a lifesaver! I keep it in my bag... Highly recommend."

Arielle E.

Verified Evvy User

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FAQ's for Anti-Itch Vulva Cream

For more, visit our Help Center

Which cream is best for vaginal itch?

When selecting a best cream for vaginal itching, look for products that combine proven active ingredients with soothing agents, like Evvy’s Anti-Itch Vulva Cream. Hydrocortisone is a commonly recommended ingredient for its anti-inflammatory properties, which can alleviate itching and irritation. Additionally, creams that incorporate moisturizers like aloe and Vitamin E can help soothe sensitive skin. It's important to choose a product that is free from harsh chemicals and fragrances to minimize the risk of further irritation, which is why Evvy’s formulations are all compounded with clean ingredients and no harsh additives.

How do you stop itching down there at night immediately?

Quick relief from nighttime vaginal itching can be achieved by applying a topical cream containing hydrocortisone like Evvy’s Anti-Itch Vulva Cream, which works to reduce inflammation and soothe the skin. Wearing loose, breathable cotton underwear (or skipping underwear altogether!) can also help reduce irritation during the night. If symptoms persist, consult your healthcare provider or take an Evvy test to uncover underlying causes and receive a personalized care plan from our expert healthcare platform.

What is the best medicine to stop itching?

Topical hydrocortisone creams like Evvy’s Anti-Itch Vulva Cream are widely recognized for their effectiveness in stopping itching due to their anti-inflammatory properties. For vaginal itching, it's crucial to use a formulation specifically designed for the vulvar area to ensure safety and efficacy (that’s why we work with a specialty pharmacy on all our formulations!). Combining hydrocortisone with soothing agents like aloe and Vitamin E can enhance comfort and provide rapid relief. By choosing a thoughtfully formulated cream that addresses both the symptoms and the sensitive nature of the vaginal area, you can find effective relief from itching and discomfort.

Are these treatments prescribed by a provider?

Yes, all treatments are prescribed by a provider and compounded at a 503a NABP-accredited pharmacy. If there is a mismatch between what you request and what the provider recommends, we will confirm with you before shipping.

Do these treatments require a live video or phone call with a provider?

Nope! To ensure that our customers are able to get care in a convenient and affordable way, Evvy-affiliated providers offer asynchronous consultations. This means your provider will review your results and intake without requiring a phone or video call. If your provider has any questions, we will reach out to you over email before prescribing. Research shows that there's no significant difference between async and in-person/live consultations in terms of treatment outcomes — but it's something we're looking into offering in the future for those who want it.

What's the difference between the Evvy Complete Treatment Program and Evvy's individual Rx products?

The Evvy Complete Treatment Program is only available after taking an Evvy test, and offers a fully personalized, multi-step care plan based on your unique vaginal microbiome results. It combines targeted medication, symptom relief products, and probiotics into one coordinated approach, complete with 1:1 coaching and progress tracking. This integrated program optimizes both immediate relief and long-term balance, unlike standalone Rx treatments that typically target a single symptom.

For those looking to soothe discomfort while waiting to test, Evvy’s prescription symptom relief products are a great option. These treatments offer effective relief for common symptoms like itching and dryness, making them ideal for anyone seeking comfort before diving into a more comprehensive care plan.

What is the difference between Evvy's treatments from what I can get from my doctor or what I can get over the counter?

Evvy’s treatments are formulated based on years of research plus our unique R&D on the vaginal microbiome, with insights from over 7,000 individuals to determine what truly works for vaginal health. Our treatments are prescription-grade and carefully compounded with the highest quality, non-toxic ingredients to ensure effective, targeted relief. Unlike standard treatments, Evvy’s formulations also consider the form factor and delivery method, optimizing each treatment to work safely and effectively with your body. Our platform offers a fully personalized experience, from expert-reviewed treatment recommendations to ongoing support, so you’re not just addressing symptoms—you’re actively supporting your long-term vaginal health.

The Evvy platform has helped 75,000+ people take control of their vaginal health

I am so thankful for Evvy’s treatment plan and guidance... Evvy’s approach felt much more comprehensive and I finally have relief after years of struggling.

Graciela

Verified Customer

Evvy actually saved my life. I couldn't be more happy with the detailed test results, relevant and cutting-edge information, and immense support.

Pia

Verified Customer

The level of detail in test results is unlike anything I could ever access through my doctor’s office... and [Evvy] dramatically changed my health.

Verified Customer

For the first time since developing symptoms, I felt heard, understood, and cared for. I could cry from happiness!

Hannah

Verified Customer