Hyaluronic Acid Suppositories

Hyaluronic Acid Suppositories

Hydrate & rejuvenate the vaginal lining for long-lasting, hormone-free relief from vaginal dryness, itching, and painful sex.

Our formulation is simple but powerful: it combines a moisturizing base with prescription-grade hyaluronic acid, a naturally-occurring molecule shown to promote hydration and elasticity, with no harsh irritants or additives.

Ideal for all life stages, whether you're dealing with dryness from hormonal fluctuations (like in menopause) or from medications (like certain birth controls).

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12 suppositories · $4.92/each

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$59

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HSA/FSA Eligible

This is a prescription product. A licensed, Evvy-affiliated provider will determine your prescription at their sole discretion.

Ingredients

5mg hyaluronic acid, moisturizing base of fatty acids

Allergen information: Our Moisturizing Base is coconut oil free but the formulation does contain palmitic acid. Palmitic acid may come from palm or coconut sources and is not suitable for individuals with coconut allergies.

How to Use

Insert 1 vaginal suppository 2-3 times per week as needed to alleviate vaginal dryness or vaginal irritation.

Do not ingest orally — for vaginal use only. Pause other vaginal treatments when using. Use within 180 days of purchase. Note: Refrigeration required to maintain firmness for insertion.

Quality

For our Rx Symptom Relief Products, we use only prescription-grade, non-toxic ingredients that are free from harmful additives.

Non-Toxic
No PFAs
No Parabens
No BPAs
No Phthalates
No GMOs
No Sulfites
No Artificial Colors/Fragrances/Dyes

Please note that this Rx Product is designed to support vaginal health, but is not prescribed to treat an underlying condition. Evvy’s Vaginal Microbiome Test and Treatment Programs can diagnose and treat the root causes of symptoms.

This is a compounded medication, formulated in a 503a NABP-accredited pharmacy. Compounded products are not approved by the FDA.

Eligibility

Your specific prescriptions will be determined at the sole discretion of an Evvy-affiliated provider. To ensure safe, compliant, and personalized care, we cannot prescribe this treatment for patients who are:

Pregnant
Breastfeeding
Younger than 18 or older than 80 years old

This treatment is not yet available in Canada or the following US states: Arkansas, Delaware, Kansas, Kentucky, Mississippi, New Mexico, Puerto Rico, Rhode Island, South Carolina, Vermont, US Virgin Islands, Washington DC, West Virginia, Armed Forces Europe / Pacific

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developed by researchers + OB/GYNs

Uniquely formulated for women

science-backed ingredients

No harsh additives

Why Hyaluronic Acid

Relieve dryness, hormone-free

Gently repair with targeted, hormone-free relief

Deeply hydrate for long-lasting comfort

Soothe irritation and inflammation

Why our formulation

Prescription-grade hyaluronic acid you can’t get over the counter

Hyaluronic Acid

Delivers advanced hydration

Prescription-grade hyaluronic acid binds up to 1,000 times its weight in water, deeply hydrating vaginal tissue to relieve dryness, itching, and irritation without hormones. In multiple clinical studies, hyaluronic acid was generally found to be effective in improving vulvovaginal symptoms like painful sex, itching, burning, vaginal dryness, pH balance and atrophy.

Moisturizing, pH-Balanced Base

Hydrates & moisturizes

Our moisturizing base has a unique blend of fatty acids that help maintain hydration while restoring vaginal pH.

Backed by science & designed by OB-GYNs

From a study on post-menopausal women (Chen 2013):

84%

reported an improvement in vaginal dryness.

86%

reported less vaginal itching and burning.

57%

reported less painful sex.

How It Works

Step 1

Order your Rx from Evvy

All Evvy prescription (Rx) products are custom compounded at a 503a NABP-accredited pharmacy, ensuring high-quality, clean ingredients.

Step 2

Complete your intake form

A licensed, Evvy-affiliated provider will review your order and intake form within 24 hours. We’ll reach out to you over email if there are any questions.

Step 3

Rx shipped to your door

If prescribed, your prescriptions will be shipped straight to you and typically arrive within 3-6 business days.

Step 4

Test with Evvy for root cause

Evvy’s products are designed to relieve symptoms, not treat underlying conditions. Taking an Evvy test gives you a complete picture of your vaginal health and empowers you to address root causes, not just symptoms.

From the community

Providers and patients choose Evvy

"Evvy’s Hyaluronic Acid Suppositories offer advanced, hormone-free hydration to help relieve dryness, vaginal atrophy, and pain with sex. Made with only prescription-grade hyaluronic acid and a simple moisturizing base, it's a gentle yet effective option for those seeking lasting comfort."

Dr. Kate McLean, MD, MPH, FACOG

Chief Medical Officer, Evvy

“The Hyaluronic Acid Suppositories and the Soothing Vulva Cream were all great products for me that were also a part of my treatment plan! I have used other products in the past that did nothing and even Rx that was prescribed by my OBGYN that did not help at all. Thank you so much for your help and support!! And treatment that actually helps!”

Ashley

Verified Evvy User

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FAQ's for Hyaluronic Acid Suppositories

For more, visit our Help Center

What are the benefits of hyaluronic acid suppositories?

Hyaluronic acid suppositories are designed to deeply hydrate and soothe the vaginal lining, offering hormone-free relief from dryness, itching, and discomfort. This powerful molecule can hold up to 1,000 times its weight in water, making it ideal for restoring moisture and elasticity in vaginal tissue. Evvy’s Hyaluronic Acid Suppositories are formulated to deliver long-lasting hydration safely and effectively.

Does hyaluronic acid help vaginal dryness?

Yes, hyaluronic acid is a proven solution for vaginal dryness and has been extensively studied in scientific research. Hyaluronic acid provides deep hydration without the use of hormones. Its ability to bind and retain moisture helps to relieve dryness and soothe irritation, making it a safe option for people experiencing dryness from menopause, postpartum changes, or medications. Evvy’s Hyaluronic Acid Suppositories are prescription-grade and uniquely designed to deliver lasting relief from vaginal dryness.

Are these treatments prescribed by a provider?

Yes, all treatments are prescribed by a provider and compounded at a 503a NABP-accredited pharmacy. If there is a mismatch between what you request and what the provider recommends, we will confirm with you before shipping.

Do these treatments require a live video or phone call with a provider?

Nope! To ensure that our customers are able to get care in a convenient and affordable way, Evvy-affiliated providers offer asynchronous consultations. This means your provider will review your results and intake without requiring a phone or video call. If your provider has any questions, we will reach out to you over email before prescribing. Research shows that there's no significant difference between async and in-person/live consultations in terms of treatment outcomes — but it's something we're looking into offering in the future for those who want it.

What's the difference between the Evvy Complete Treatment Program and Evvy's individual Rx products?

The Evvy Complete Treatment Program is only available after taking an Evvy test, and offers a fully personalized, multi-step care plan based on your unique vaginal microbiome results. It combines targeted medication, symptom relief products, and probiotics into one coordinated approach, complete with 1:1 coaching and progress tracking. This integrated program optimizes both immediate relief and long-term balance, unlike standalone Rx treatments that typically target a single symptom.

For those looking to soothe discomfort while waiting to test, Evvy’s prescription symptom relief products are a great option. These treatments offer effective relief for common symptoms like itching and dryness, making them ideal for anyone seeking comfort before diving into a more comprehensive care plan.

What is the difference between Evvy's treatments from what I can get from my doctor or what I can get over the counter?

Evvy’s treatments are formulated based on years of research plus our unique R&D on the vaginal microbiome, with insights from over 7,000 individuals to determine what truly works for vaginal health. Our treatments are prescription-grade and carefully compounded with the highest quality, non-toxic ingredients to ensure effective, targeted relief. Unlike standard treatments, Evvy’s formulations also consider the form factor and delivery method, optimizing each treatment to work safely and effectively with your body. Our platform offers a fully personalized experience, from expert-reviewed treatment recommendations to ongoing support, so you’re not just addressing symptoms—you’re actively supporting your long-term vaginal health.

The Evvy platform has helped 75,000+ people take control of their vaginal health

I am so thankful for Evvy’s treatment plan and guidance... Evvy’s approach felt much more comprehensive and I finally have relief after years of struggling.

Graciela

Verified Customer

Evvy actually saved my life. I couldn't be more happy with the detailed test results, relevant and cutting-edge information, and immense support.

Pia

Verified Customer

The level of detail in test results is unlike anything I could ever access through my doctor’s office... and [Evvy] dramatically changed my health.

Verified Customer

For the first time since developing symptoms, I felt heard, understood, and cared for. I could cry from happiness!

Hannah

Verified Customer